gwu school of engineering

Welcome to BDL

Overview

Located on the Foggy Bottom campus of The George Washington University, within the Department of Mechanical and Aerospace Engineering (MAE), the Biofluid Dynamics Lab (BDL) is directed by Professor Michael W. Plesniak. Research in the BDL focuses on experimental in vitro investigations of unsteady, viscous physiological flows. Most processes within the body involve laminar, or non-turbulent fluid flow, but aeroacoustics of speech and pathological blood flow through arteries are rare exceptions that offer a wealth of challenging fluid dynamics issues.

Coronal section of the vocal folds during one phonatory cycle.

Plaque deposits in the coronary artery pose a significant risk for both stroke and heart disease. Our physiological blood flow investigations seek to determine the mechanisms that lead to the build-up of plaque deposits in the coronary artery by identifying the formation of secondary flow structures in curved in-vitro models. It is hypothesized that the presence of secondary flow structures will diminish clotting and platelet deposition due to increased mixing. Future investigations are planned to evaluate the efficacy of stent implants and ascertain the physiological response that arises due to the modified flow field.

Severe stenosis in the coronary arteryThe BDL is equipped with advanced flow measurement and visualization systems, cameras and non–invasive, optical, diagnostics such as particle image velocimetry (PIV) and laser Doppler velocimetry equipment provides capabilities to perform microscopic flow measurements and analysis systems. The goal of the research performed in this lab is to assess the role of flow-induced interactions in the human body through experiments, and also partner with clinicians to provide solutions that will aid in diagnosis and treatment of common pathologies. including high-speed (LDV). This both macroscopic and in complicated flow in vitro experiments, and also partner with clinicians to provide solutions that will aid in diagnosis and treatment of common pathologies.

Contact Info

For more information, please contact Dr. Plesniak at plesniak@gwu.edu or Kartik Bulusu at bulusu@gwmail.gwu.edu.